This presentation presents IVS4 concept, an integrated system combining Action Observation (AO), Motor Imagery (MI), and Mirror Therapy (MT) to exploit mental repetition as a boost for neuroplasticity. By activating shared motor networks via mental simulation, these techniques induce plasticity, bypassing physical limitations to accelerate motor recovery.

We present clinical evidence validating IVS4 efficacy in lower limb and gait rehabilitation across various pathologies, highlighting device-specific outcomes. Implementation frameworks for clinical adoption are discussed, including synergistic integration with other techniques.

Lisa Stahlhofen (Kliniken Valens) supplements these findings with a pain management case report and an innovative research program combining IVS4 with robotic gait training, demonstrating all the potential of such approach in day-to-day practice.